NRNB: GeStoDifferent

GeStoDifferent

GeStoDifferent is a Cytoscape app aimed at the generation and the identification of gene regulatory networks describing an arbitrary stochastic cell differentiation process.

Documentation

How to Cite

GeStoDifferent: a Cytoscape plugin for the generation and the identification of gene regulatory networks describing a stochastic cell differentiation process. Antoniotti et al., Bioinformatics 2013.

Image Gallery

Example screenshot of the GeStoDifferent app.
Example workflow of GeStoDifferent.

Example differentiation tree. The descendent of a unique stem cell type are two distinct differentiated cell types.
Schematic representation of the crypt differentiation tree. Stem cells are the root of the tree, while the 4 differentiated cell types (i.e. Paneth, Goblet, enteroendocrine, absorptive or enterocyte) are the leaves.